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| Acta Biomed Ateneo Parmense 1984;55(1):5-14 |
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Dietary fiber and OGTT:
blood sugar variations after administration of a new purified
glucomannan
[Article in Italian]
Magnati G, Arsenio L, Bodria P, Lateana M, Strata A.
After having stressed the importance of fibres in the nutritional
field, pointing out the inverse relationship between vegetal
fibres consumption in various populations and diffusion of many
diseases of the so-called "industrialized" societies (such as
obesity, diabetes, dyslipidemias, atherosclerosis, cholelithiasis,
cancer of the colon, etc.), the Authors report their experiment
on a new experimental product based on glucomannane purified
(PRL). The present study was carried out on 24 obese subjects
(5 males and 19 females). The patients, normoglycemics in their
basic condition, were submitted to OGTT with 75 g of glucose
in the morning before eating and were subdivided into two groups,
the first (Group A) characterized by the sequence OGTT + placebo;
after a few days, by another OGTT + experimental product; the
second characterized by the inverse sequence. Four tablets (glucomannane
purified 5,2 g) and four tablets of placebo was the posology
employed. The evaluation of the possible action of the product
in reducing or slowing down the intestinal absorption of glucose
was the aim of the research. The results obtained show that
the administration of the product under study has led to a sharp
decrease of the average glycemic values with variations per
cent ranging from 13% to 16% in Group A, from 10% to 11% in
Group B and from 7% to 12% in the two groups considered on the
whole. In conclusion, the Authors wish an increased diffusion
of dietary fibres and particularly of the glucomannanes in all
those dysmetabolic forms having at their bases an unbalanced,
hypercaloric alimentation, rich in refined aliments and poor
in fibres.
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